A Pan-pangenome illuminates complex structural variation and selection in humans, chimpanzees, and bonobos
This study presents a high-quality, population-scale pangenome resource of 58 haplotypes from chimpanzees and bonobos that reveals extensive structural variation, highlights parallel adaptations to malaria via glycophorin gene fusions, and underscores the critical role of nonhuman primate pangenomics in understanding human genome evolution and biodiversity.